Proteomics and Metabolomics
Mass spectrometry-based computational approaches for large-scale identification, quantification, and functional characterization of proteins and metabolites
Overview
Proteomics and metabolomics complement genomics by directly measuring the functional molecules in cells. Computational analysis of mass spectrometry data identifies and quantifies thousands of proteins and metabolites simultaneously.
Key Topics
- Database searching and de novo peptide sequencing
- Label-free and isotope-labeled quantification
- Post-translational modification (PTM) analysis
- Metabolite identification and pathway mapping
- Multi-omics data integration (proteome + metabolome)
- Structural proteomics (cross-linking MS)
Applications
- Biomarker discovery for disease
- Drug mechanism of action
- Plant secondary metabolite profiling
- Clinical diagnostics
Faculty in This Area (7)
Assistant Professor
Chatchai Phoomak, Ph.D.
Assistant Professor
Chompoonik Kanchanabanca, Ph.D.
Department of Microbiology, Faculty of Science
Associate Professor
Kunlaya Somboonwiwat, Ph.D.
Department of Biochemistry, Faculty of Science
Lecturer
Pasrawin Taechawattananant, Ph.D.
Professor
Supaart Sirikantaramas, Ph.D.
Department of Biochemistry, Faculty of Science
Professor
Taninee Sahakitrungruang, M.D., Ph.D.
Department of Pediatrics, Faculty of Medicine
Lecturer
Thiti Suttiyut, Ph.D.
Department of Botany, Faculty of Science