Microbiome and Metagenomics

Analysis of microbiome composition and metagenomic data from environmental or clinical samples using 16S rRNA profiling and whole-metagenome shotgun sequencing

Microbiome and Metagenomics

Overview

Metagenomics enables the study of entire microbial communities without requiring individual cultivation. This research area covers the computational pipelines and statistical methods needed to characterize microbial diversity and function.

Key Topics

  • 16S rRNA amplicon sequencing and OTU/ASV analysis
  • Whole-metagenome shotgun sequencing
  • Microbiome diversity indices (alpha/beta diversity)
  • Functional gene profiling and pathway analysis
  • Host-microbiome interaction analysis
  • Long-read metagenomic assembly

Applications

  • Gut microbiome and human health
  • Environmental monitoring
  • Infectious disease epidemiology
  • Agricultural soil microbiome studies